环烷基磺酰胺类化合物对拟轮枝镰孢菌抑制作用及伏马菌素生物合成基因表达的影响

采用菌丝生长速率法,以惡霉灵原药为对照药剂,从62种环烷基磺酰胺类化合物中筛选出436、MSQ8和WML-1等3种对拟轮枝镰孢菌菌丝生长有明显抑制作用的化合物,其EC50分别为11.42 μg/mL、20.85 μg/mL和33.76 μg/mL,高于或接近于对照药剂惡霉灵的EC50 (20.77 μg/mL)。对拟轮枝镰孢菌分生孢子萌发抑制试验结果表明,化合物WML-1、MSQ8和436的EC50分别为165.25 μg/mL、185.12 μg/mL和274.46 μg/mL,均低于对照药剂噁霉灵的EC50(65.81 μg/mL)。qRT-PCR结果表明,3种药剂处理后对伏马菌素的生物合成基因表达无明显影响。 英文摘要: Mycelium growth rate of Fusarium verticillioides was tested by hymexazol and 62 novel cycloalkyl sulfonyl compounds.Among them, compounds 436, MSQ8和WML-1 were three kinds of the most effective compounds that could inhibit the mycelium growth of F.verticillioodes, with the EC50 values of 11.42 μg/mL, 20.77 μg/mL and 33.76 μg/mL, respectively. Inhibit effect was higher than or close that of control fungicide. They were not demonstrated inhibitory effects on conidia germination, with the EC50 values of 165.25 μg/mL, 185.12 μg/mL and 274.46 μg/mL, inhibit effect was lower than that of control fungicide. qRT-PCR results showed that 3 compounds did not inhibit Fumonisins biosynthesis. 查看全文
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