PNAS:福建农林大学吴双研究组等揭示植物细胞沟通机制与促根系
2016年9月23日，国际著名学术期刊《美国国家科学院院刊》杂志在线发表了美国宾夕法尼亚大学Kimberly L. Gallagher教授和福建农林大学青年千人计划吴双教授合作的题为《Symplastic signaling instructs cell division, cell expansion, and cell polarity in the ground tissue of ArABIdopsis thaliana roots》的研究论文，研究揭示了植物细胞沟通机制与对根系发育的调控作用。吴双教授论文第一作者与共同通讯作者，Kimberly L. Gallagher教授为另一通讯作者。
细胞间的信号交流对于动植物组织器官的正确发育至关重要。由于缺乏有效的分析工具，植物细胞间如何进行信号交流，并且胞间交流如何影响发育长期以来并不清楚。吴双课题组利用一种全新的方法有效地调控植物胞间连丝的通透，从而发现通过胞间连丝介导的信号交流在植物根系发育中决定了基本组织的细胞分裂和细胞伸长模式，同时也决定了该组织中细胞极性的维持。通过上述研究不仅确定了胞间连丝在发育中作为信号通道的重要作用，而且对进一步理解植物根系发育的时空调控具有重要意义。
原文链接：
Symplastic signaling instructs Cell division, cell expansion, and cell polarity in the ground tissue of Arabidopsis thaliana roots
原文摘要：
Cell-to-cell communication is essential for the development and patterning of multicellular organisms. In plants, plasmodesmata (PD) provide direct routes for intercellular signaling. However, the role that PD-mediated signaling plays in plant development has not been fully investigated. To gain a comprehensive view of the role that symplastic signaling plays in Arabidopsis thaliana, we have taken advantage of a synthetic allele of CALLOSE SYNTHASE3 (icals3m) that inducibly disrupts cell-to-cell communication specifically at PD. Our results show that loss of symplastic signaling to and from the endodermis has very significant effects on the root, including an increase in the number of cell layers in the root and a misspecification of stele cells, as well as ground tissue. Surprisingly, loss of endodermal signaling also results in a loss of anisotropic elongation in all cells within the root, similar to what is seen in radially swollen mutants. Our results suggest that symplastic signals to and from the endodermis are critical in the coordinated growth and development of the root.
作者：吴双
